Essay on Synthesis of Aspirin - 5275 Words

The Synthesis of Aspirin Chemistry Standard Level Lab Report Data Collection and Processing and Conclusion and Evaluation Date: December 8th, 2011 Purpose: The purpose of this lab was to synthesize aspirin, determine the theoretical yield, compare the percent yield to the theoretical yield and test the purity of aspirin by adding Iron (III) chloride to the product. Hypothesis: I hypothesize that salicylic acid will react with acetic anhydride to produce acetylsalicylic acid (aspirin) and acetic acid (vinegar). Variables: Independent and controlled variables: The amount of sulfuric acid used for catalysis and the amount of salicylic acid and acetic anhydride. Dependent variables: Theoretical and actual yield of†¦show more content†¦The aspirin crystals were washed by pouring 10 mL of water over them through the funnel. The filter paper, holding the aspirin crystals, was removed from the funnel and was left to dry before being weighed. Once the aspirin crystals were weighed, the theoretical yield and the percent yield of the experiment were calculated. The procedure was repeated once more using the same steps. Procedure for the test of purity of aspirin: 0.1 gram of salicylic acid was weighed in a tray and was then added to a test tube containing 2.0 mL of Iron (III) chloride, which was measured using a 10 mL graduated cylinder, to test for phenols. 0.1 gram of commercial aspirin was weighed in a tray and was then added to a second test tube containing 2.0 mL of Iron (III) chloride, which was measured using a 10 mL graduated cylinder, to test for phenols. This was repeated once more to validate results. 0.1 gram of my product from the first trial was weighed in a tray and was then added to a third test tube containing 2.0 mL of Iron (III) chloride, which was measured using a 10 mL graduated cylinder, to test for phenols. This was repeated once more to validate results. 0.1 gram of my product from the second trial was weighed in a tray and was then added to a fourth test tube containing 2.0 mL of Iron (III) chloride, which was measured using a 10 mL graduated cylinder, to test forShow MoreRelatedSynthesis Of Aspirin Synthesis825 Words   |  4 PagesSynthesis of Aspirin Erin Chase Arellano CHEM 12A ABSTRACT Acetylsalicylic or most commonly known as Aspirin is made through a combination of salicylic acid and acetic anhydride. It is use to relieve mild to moderate pain such as muscle pain, headaches and common cold and reduce fever. The objective of this experiment was to synthesize aspirin from salicylic acid and acetic anhydride. The purity of aspirin was tested using the ferric chloride test and % yield was also calculated. Below drawingRead MoreSynthesis of Aspirin1618 Words   |  7 Pagesobjective was to convert a specific amount of salicylic acid into the same amount of aspirin that was high in purity. 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Faculty of Engineering University of Santo Tomas Manila, Philippines ABSTRACT This experiment involved three steps: synthesis of aspirin, isolation and purification, and the estimation of purity of the final product. The synthesis involved the reaction of salicylic acid and acetic anhydride in the presence of a catalyst, phosphoric acid, H3PO4. When the aspirin was prepared, it was isolated and filtered. The percentageRead MoreThe Theory Of Green Chemistry On Microwave Heating Essay1532 Words   |  7 PagesObjective The current experiment introduces the concept of green chemistry on microwave heating to synthesise aspirin, instead of using conventional heating methods. Introduction Aspirin synthesis is a popular experiment undertaken in most organic chemistry teaching laboratories (Montes et al., 2006). Most experimental procedures for aspirin synthesis are undertaken to study the carbonyl nucleophilic substitution reactions either under basic or acidic conditions (Polshettiwar and Varma, 2008; VarmaRead MoreThe Synthesis Of A Medicinal Agent Essay938 Words   |  4 PagesThe Synthesis of a Medicinal Agent – Aspirin IDC 3002H – EMWH Dylan Chow 9/14/2016 Abstract: In this experiment, aspirin was synthesized from a reaction between salicylic acid and acetic anhydride. Acetic anhydride was added to salicylic acid to create a solution and phosphoric acid was added to catalyze the reaction. After the salicylic acid was fully dissolved in a boiling water bath, water would be added to decompose the remaining acetic anhydride. Through the process of filtration, aspirin